Islet Preconditioning via Multimodal Microfluidic Modulation of Intermittent Hypoxia
نویسندگان
چکیده
منابع مشابه
Islet preconditioning via multimodal microfluidic modulation of intermittent hypoxia.
Simultaneous stimulation of ex vivo pancreatic islets with dynamic oxygen and glucose is a critical technique for studying how hypoxia alters glucose-stimulated response, especially in transplant environments. Standard techniques using a hypoxic chamber cannot provide both oxygen and glucose modulations, while monitoring stimulus-secretion coupling factors in real-time. Using novel microfluidic...
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ژورنال
عنوان ژورنال: Analytical Chemistry
سال: 2012
ISSN: 0003-2700,1520-6882
DOI: 10.1021/ac2030909